Editor-in-Chief: Roger O. McClellan, Albuquerque, New Mexico, USA

From subjects that form the advancing frontiers of toxicology to those that make up the core of some of the most complex and intractable problems in toxicology, Critical Reviews in Toxicology covers the field. The journal provides objective analyses of crucial topics related to the mechanisms, responses, and assessments of toxicants. Articles include coverage of commodity and specialty chemicals such as formaldehyde, acrylonitrile and pesticides; pharmaceutical agents of all types; consumer products such as macronutrients and food additives; and environmental agents such as ozone and dioxin. Toxicological responses reviewed include effects from subtle physiological alterations to overt toxicity manifested in major systems, e.g. respiratory, gastrointestinal, endocrine, urogenital, musculoskeletal, nervous, hematopoietic, and immunological. Particular attention is given to cancer and developmental effects as responses of special societal concern. Mechanisms of action at all levels of biological organization are addressed—from macromolecules and cells up to integrated organisms and populations of laboratory animals and people.

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Editorial Advisory Board:

Hermann M. Bolt – Institut für Arbeitsphysiologie, an der Universität Dortmund, Dortmund, Germany

Philippe Grandjean – Environmental Medicine - Institute of Community Health, Odense University, J. B. Winslows Vej 19, DK-5000 Odense C, Denmark

F. Peter Guengerich – Department of Biochemistry - Center for Toxicology, Vanderbilt University, School of Medicine, 21 Avenue South & Garland, Nashville, TN 3723

Charles F. Reinhardt - Haskell Laboratory, E. I. duPont de Nemours & Co., Elkton Road, Newark, DE 19711

Bernard A. Schwetz – National Center for Toxicological Research, HFT-1, 3900 NCTR Road, Jefferson, AR 72079-9502

Yasuhiko Shirasu – Institute of Environmental Toxicology, Tokyo, Japan

Shuji Tsuda – Hoechst Japan Limited, Pharma Research Laboratories, 3-2, Minamidai 1-chome, Kawagoe, Saitama 350 Japan

Peter A. Ward – Pathology/Medical Science, I-M5240/0602, University of Michigan Medical School, 1301 Catherine Drive, Ann Arbor, MI 48109